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Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development

ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances (14)

Again, not resolving the actual problem

To address this limitation, hydrogels incorporated with metal-based nanozymes exhibiting CAT-like activity, such as copper selenide NPs or MOFs, can sustainably decompose endogenous H 2 O 2 abundantly present in the TME to generate oxygen in situ , thereby effectively alleviating tumor hypoxia

Is It Safe

Bioinformatics 22, 195201 (2006)