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Clinical Evidence: Several studies support the potential of BPC-157 in correcting calcium imbalance: a) A study published in the Journal of Orthopaedic Research demonstrated that BPC-157 administration improved bone healing and increased calcium deposition in rats with induced bone fractures, suggesting its positive effect on calcium metabolism

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Conversely, downregulation of FABP4 by apelin/apelin receptor (APLNR)-mediated Forkhead box O1 (FOXO1) suppression in ECs limits excessive FA transport and tissue accumulation, contributing to atheroprotecton against vascular diseases such as atherosclerosis [86,87,88]