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GSSG sensitized hepatocytes to TNF-mediated cytotoxicity via the induction of IKK- glutathionylation and subsequent NF-B suppression NF-B activation plays a critical role in protecting hepatocytes from TNF-mediated cytotoxicity

References Averill-Bates DA

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The study, available online in Nature, shows that people who were repeatedly vaccinated for COVID-19 initially receiving shots aimed at the original variant, followed by boosters and updated vaccines targeting variants generated antibodies capable of neutralizing a wide range of SARS-CoV-2 variants and even some distantly related coronaviruses