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BPC-157's strength in promoting angiogenesis and modulating nitric oxide pathways pairs with TB-500's actin-regulatory functions that facilitate cellular movement and tissue reorganization

As summarized in the same 2013 review, the pre-specified primary endpoint for statistically significant weight change across the dose range and study duration was not met, even as the safety and tolerability picture held [7]

This may be due to patients being in the early stages of ALS and not showing rapid progression, the team noted

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