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In OASIS 4, gastrointestinal effects affected around 74% of those on the Wegovy pill compared with 42% on placebo, led by nausea (roughly 47% vs 19%) and vomiting (about 31% vs 6%), with diarrhoea and constipation also common

Semaglutide is a synthetic version of a naturally occurring hormone called GLP-1, which helps regulate blood sugar

You should stop using WEGOVY 2 months before you plan to become pregnant

This reduced excitability is likely mediated by a shunting mechanism, 16 whereby increased tonic GABA conductance lowers membrane resistance and dampens depolarization from excitatory inputs without altering EPSP amplitude

This improves glucose metabolism and therefore blood glucose levels in people with type 2 diabetes

in REDEFINE 2 (type 2 diabetes), about 13.7%