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PAHs are specifically emitted from the process of incomplete combustion of carbon sources such as vehicles, coal burning units, and gasoline derivatives

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So someone can have a strong family history, metabolic dysfunction, discordantly high apoB, early scans suggesting disease, and a high risk cumulative exposure picture and still look "low risk" in a short-term model due to their age

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FEMS Microbiol Rev 45:fuaa061 Kramnik I, Beamer G (2016) Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies