While all GLP-1 medications may promote some weight loss, three drugs are specifically indicated for chronic weight management: Zepbound (tirzepatide) Wegovy (semaglutide) Saxenda (liraglutide) Multiple clinical trials have found that each of these medications can help people lose 5%-20% or more of their body weight though research suggests that some may be more effective than others
In the SURMOUNT clinical trial program, participants receiving Zepbound at the highest dose (15 mg) lost an average of approximately 21 percent of their body weight
Kaitlin Sullivan Author Joseph Bennington-Castro Author Joseph Bennington-Castro is a science writer based in Hawaii
The Clayman researchers analyzed data from clinical trials, adverse event reports, and large studies of real-world patients
NF-B signaling pathway The NF-B signaling pathway plays a pivotal role in biological processes such as the immune response, cell proliferation, and apoptosis
Toxicon: official journal of the International Society on Toxinology 60, 596602, doi: 10.1016/j.toxicon.2012.05.027 (2012)