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Various animal studies have demonstrated the key role of inositol in bone health, with a lack of inositol causing a reduction of bone mineralization and the supplementation of inositols, positively modulating the balance between bone-producing and bone-removing cells [83, 84]

Intervention Randomly assigned 1:1 to subcutaneous Semaglutide 2.4 mg once-weekly for 52 weeks or placebo Semaglutide treatment was initiated at a dose of 0.25mg once-weekly for the first 4 weeks

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