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At normal, therapeutic levels, this byproduct is easily deactivated when it binds to a naturally occurring, protective molecule called glutathione

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[DOI] [PMC free article] [PubMed] [Google Scholar] 309.Attard GPC, Eeles RA, Schrder F, Tomlins SA, Tannock I, Drake CG, de Bono JS

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Oxidized low-density lipoprotein (ox-LDL) induces ferroptosis in macrophages and endothelial cells, releasing pro-inflammatory lipid mediators that recruit additional immune cells and perpetuate vascular inflammation