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While the numbers are startling, researchers are conducting studies to understand why the trend appears to lean toward one sex, especially as one in five Americans is at risk of developing an autoimmune disease at some point in their lives

When side effects do occur, they are often mild and related to the injection itself, such as redness, pain, or swelling at the injection site

Separate high-dose oral b12 (1000 to 2000 mcg daily) or regular b12 injections (1000 mcg weekly or monthly) offer more reliable repletion

These findings indicate that carboplatin induces both apoptotic cell death and a proinflammatory response in ovarian tissue