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Key words: L-carnitine, Orlistat, Insulin resistance, HOMA-IR, Type 2 diabetes side effects that usually attenuate with the prosecution of the treatment but often not acceptable from the pa- tients [3] and some pharmacokinetic interactions that are rare but potentially relevant, with cyclosporin [4] and warfarin [5]

Starting with a lower dose and increasing it slowly over several weeks allows the body to adapt, reducing the intensity of these reactions

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Some patients see steady improvement and transition from weekly treatments to monthly maintenance, while others may continue to benefit from regular injections to help ease symptoms and support overall health

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