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Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

In laboratory testing, it did not inhibit related SAM-dependent methyltransferases or interfere with other enzymes in NAD+ salvage pathways

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Lifespan data Published rodent longevity studies from Khavinson's group report epitalon extending median and maximum lifespan by 1224%, alongside reduced tumor incidence rates