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Patients starting semaglutide are often already on metformin or proton pump inhibitors (which block tablet absorption)

These adjustments commonly include fatigue as a transient symptom

Vitamin B 6 was included in the medication Bendectin (a delayed-release formulation of 10 mg doxylamine succinate [an antihistamine] and 10 mg pyridoxine hydrochloride [vitamin B 6 ]), which was prescribed for the treatment of morning sickness and later withdrawn from the market in 1983 due to unproven concerns that it increased the risk of birth defects (80)

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