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The third cluster (green) displayed gene expression compatible with more PUFA incorporation into membranes but also upregulation of ferroptosis defenses, while the second cluster (red) comprises MASLD patients with ferroptosis-sensitizing PUFA incorporation combined with lowered ferroptosis defenses (Fig

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Survival also differed significantly by MELD-3 trajectory (p 98%) and markedly reduced survival in deteriorated patients (74.3% at 1 year)

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Li H, Li C-W, Li X, Ding Q, Guo L, Liu S, Liu C, Lai C-C, Hsu J-M, Dong Q, et al