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some protocols specify fasted administration to optimize absorption, while others note minimal food effects

Melatonin has been found to be safe and associated with little or no side effects (Gagnier 2001

Brief temperature excursions during transport from the refrigerator to injection are fine, but the vial should not sit at room temperature for extended periods

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In women, added pounds can contribute to insulin resistance and elevated testosterone levels, which can stifle ovulation

The spot might feel a little tender for a short while afterwards, but it fades fast