This effect may be mediated by inhibiting Wnt-driven epithelial proliferation and dysfunction, and by correcting solute transport disorders that control the physiological balance of the Na + /Cl - (decreased fecal Na + and Cl - levels, increased serum Na + and Cl - levels), and reducing serum total protein [8789]
Aside from hyperhomocysteinemia, C677T or A1298C MTHFR (the two genes most studied) mutations are associated with an increased risk of other conditions including cardiovascular and thromboembolic diseases such as strokes, blood clots, and heart attacks, ADHD in children, pregnancies with neural tube defects, depression, anxiety, diabetic neuropathy, glaucoma migraines, schizophrenia, and colorectal polyps
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Statements Author contributions JD: Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing original draft, Writing review & editing
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