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& Francis, D

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We also examined the functional role of CRAT in the migration and invasion capabilities of OC cells and revealed that overexpression of CRAT led to a significant decrease of migration and invasion capabilities in HEY and SKOV3 cells, while knockdown of CRAT resulted in a clearly increase of migration and invasion capabilities in A2780 and ES2 cells

This opens the possibility of oral administration, which is particularly relevant for gastrointestinal autoimmune conditions where delivering the peptide directly to the affected tissue makes biological sense

Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure

But its not officially approved for weight loss, so keep that in mind