Gastric motility : Some studies report increased gastric motility and occasional GI discomfort, related to ghrelin's well-established role in gut motility regulation
Common experimental systems include receptor binding assays, neuronal signaling studies, metabolic animal models, and biochemical pathway analysis
Also, the lack of L-carnitine leads to fatigue and exhaustion
Repetitive behavior as assessed through percentage of marbles buried over a thirty-minute period was comparable between the control and MIA mice, with an average of 50.2 5.8 percent buried by control mice and 48.9 6.3 percent buried by MIA mice
The mechanism behind these headaches is not fully understood but may relate to the drugs effects on glucose metabolism and appetite regulation, which are integral to its therapeutic action
The absolute risk appears to be rare based on clinical trial and post-marketing data