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AGEs are final, permanent products of glycation that can modify the physicochemical properties of proteins, increase their resistance to proteolysis, and interact with RAGE receptors, causing oxidative stress and an inflammatory response 57

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In Experiment 2, to investigate the effects of induced heat stress on oocyte quality and developmental competence, an in vitro model was developed

Nutrition, Metabolism and Cardiovascular Diseases , 33(8), 1570-1579

Zhong Q, Itokawa T, Sridhar S, et al