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Shenoy R, Prabhu M, Kalthu G, S

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Semaglutide is a single agonist : it activates the glucagon-like peptide-1 (GLP-1) receptor

The UK Association of Anaesthetists published comprehensive multidisciplinary consensus in January 2025, recommending that GLP-1 receptor agonists be continued before surgery with individualised risk assessment [42]

These abnormalities not only result in impaired cholesterol transport, increased systemic oxidative stress, and endothelial dysfunction, but also lead to reduced HDL function and to the production of pro-inflammatory HDL-C, which increases the burden of atherosclerosis and cardiovascular disease [10]

Makarova E, et al