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Cell Signal 22:684696 [DOI] [PMC free article] [PubMed] [Google Scholar] Chung KY, Rasmussen SG, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL, Jr, Sunahara RK

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in Encyclopedia of Metalloproteins (eds Kretsinger, R

The origin itself explains the historical direction of research: the first area described was cytoprotection of the gastric and intestinal mucosa, and only later did the literature broaden the molecules profile to include angiogenesis and soft-tissue repair