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And this matters more than many people initially appreciate

Scientific References (External Links) Nature Chemical Biology: Small molecule inhibitors of nicotinamide N-methyltransferase View Study Biochemical Pharmacology: Nicotinamide N-methyltransferase: A promising target for treating metabolic disorders View Study FASEB Journal: Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity in mice View Study Journal of Biological Chemistry: Inhibition of nicotinamide N-methyltransferase in vivo regulates cellular energy metabolism View Study

For higher body weights, this scale can be extended even further

Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell

10.1016/s1470-2045(18)30937-30939 Lancet Oncol