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As a result, clinicians do not treat the starting doses as interchangeable, and a direct Mounjaro to Wegovy dose conversion is not considered medically appropriate
GLP-1 medications typically produce: Lower postprandial glucose peaks (post-meal spikes become flatter and shorter) Reduced fasting glucose over time as weight decreases Improved Time in Range (TIR) the percentage of time your glucose stays between 70180 mg/dL, which is the key CGM metric for diabetes management Because the oral pill is taken daily rather than weekly, the GLP-1 effect on gastric emptying may be more consistent throughout the week though individual CGM patterns will vary
While they share similarities, Mounjaro and Ozempic have some key differences, including slightly different mechanisms of action, active ingredients, dosing, and effectiveness
The fundamental technique is identical
Table 1 Comparison of guidelines for preoperative discontinuation of SGLT2 inhibitors