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Liraglutide (a daily injection) resulted in an average 4-5% weight loss in 24 trials (9 937 participants), still outperforming placebo

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While diabetes, hypertension, and sleep apnea are well-known risk factors, recent studies have identified a potential association between semaglutide-based GLP-1 medications and NAION

Chicago Arthritis's overview of GLP-1, CJC-1295, AOD-9604, and related peptides lists nausea, headaches, and fluid retention as possible side effects and stresses that any peptide plan, especially a combined or "stacked" protocol, needs to be built and monitored by a knowledgeable physician (chicagoarthritis.com)