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It is crucial to understand that while Niacin is a precursor to NAD+, many contemporary NAD+ boosting strategies involve different precursors like Nicotinamide Riboside (NR) or Nicotinamide Mononucleotide (NMN), or direct NAD+ intravenous therapies

Its principal function is to act as a cellular antioxidant, buffering lactic acid in muscles (delaying fatigue) and combating glycation, a process associated with aging and cell damage

The study also focused only on semaglutide, and the findings cannot be immediately generalized to other GLP-1 drugs

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[PMC free article] [PubMed] [Google Scholar] 56.Soares C.N., Frey B.N