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Similar content being viewed by others Introduction From 2000 to 2019, the Global Burden of Disease study showed a 0.48% annual increase in age-standardized disability-adjusted life years (DALYs) related to obesity, defined as a body mass index (BMI) 25 kg/m 2 1

This appointment catches any unexpected reactions early

However, even then, they are not usually toxic

Surgery 232 (2), 199201

Medical professionals should carefully assess your medical history, preexisting conditions, and potential drug interactions

Side Effect Profiles The most noticeable practical difference is that dual agonists like tirzepatide tend to cause slightly more gastrointestinal side effects than pure GLP-1 agonists