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The relationship between cardio-cerebrovascular diseases and mitochondrial dysfunction (Table 1) Mitochondria in cardiovascular disease There are significant differences in mitochondrial metabolism between healthy individuals and patients with CVD
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Moreover, Circadian genes also regulate angiogenesis by influencing endothelial and pericyte functions, through mechanisms such as modulation of angiogenic factors (38), basement membrane degradation (39), extracellular matrix remodeling (40), and regulation of endothelial migration, proliferation, and pericyte recruitment (41)
As studies progress, these treatments may emerge as foundational components in a comprehensive approach to mitigating the impact of diabetic kidney disease, promoting both longevity and quality of life for those facing this complex illness
7: 5749 Giugliano D, Ceriello A, Paolisso G