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Ignited by the observation of a rapid antidepressant effect of the glutamate N -methyl-D-aspartate (NMDA) receptor antagonist ketamine, the glutamate system has emerged as a leading focus for novel drug discovery for depression and other mood disorders

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The degree to which liposomal encapsulation improves cellular uptake relative to S-Acetyl L Glutathione is not known, but it is likely it crosses the blood-brain barrier more efficiently

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