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If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis

We suggest regular checks of: Serum B12 levels Methylmalonic acid (MMA) levels Complete Blood Count (CBC) These tests help doctors see if B12 is working right and adjust treatment as needed

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However, this was not sufficient to rescue the decreased lipogenic factors or decreased circulating triglycerides (Fig