Results from GLP-1 therapy can vary, but many patients start to notice improvements in blood sugar levels, appetite control, and digestion within a few weeks of starting the treatment
The infographic shared by Michael Weintraub, MD effectively summarizes the broad spectrum of systemic actions mediated by GLP-1
Crohns disease, should be excluded
doi: 10.1016/s0140-6736(16)00278-6 5 ZhangWWangXLiPZhangWWangHTangB
That might sound like a mouthful, but the concept is pretty straightforward
Contact your healthcare provider within 24 hours if you experience: Persistent vomiting (more than 24 hours) preventing adequate fluid intake Severe diarrhea (more than 6 episodes daily) lasting beyond 48 hours Inability to keep down fluids despite anti-nausea measures Weight loss exceeding 23 pounds in 24 hours (likely fluid loss) Markedly reduced urine output with dark, concentrated urine New or worsening dizziness affecting daily activities or causing falls Blood glucose readings consistently above target despite usual management Seek immediate medical attention (emergency department or call 911) for: Severe, persistent abdominal pain (may indicate pancreatitis or gallbladder disease, which are labeled risks of GLP-1 medications requiring immediate evaluation and drug discontinuation) [1] Severe dizziness or fainting episodes Rapid or irregular heartbeat with chest discomfort Confusion, disorientation, or altered mental status Inability to urinate for 12+ hours Signs of acute kidney injury (decreased urine output, swelling, severe fatigue) Symptoms of hyperglycemic emergencies in diabetes patients (excessive thirst, frequent urination, fatigue, fruity breath) Patients with pre-existing kidney disease, heart failure, or those taking multiple medications affecting fluid balance should maintain closer communication with their healthcare team
