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Two commonly discussed choices are metformin and oral semaglutide, often compared in conversations around Wegovey vs metformin for weight loss

Learn more: How Long Do The Side Effects of Wegovy Last? What precautions should I take during Wegovy treatment

Looking ahead, the next phase of obesity medicine will likely see GLP-1 medications used in combination with other weight loss agents, as well as expanded research into their effects on conditions like high blood pressure, heart attack risk, and liver disease

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The SURMOUNT-1 trial (N=2,539) reported a vomiting rate of 12.2% for tirzepatide 15 mg, lower than the 24.8% seen with semaglutide 2.4 mg in STEP 1, although cross-trial comparisons have significant limitations [16]

How does Ozempic (semaglutide) work