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doi: 10.3322/caac.21660 2 QiXLiQCheXWangQWuG

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To explore the potential effect of liraglutide on OA-associated pain, MIA OA mice models were developed

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These mechanisms lead to muscle catabolism despite caloric excess, creating a therapeutic paradox: while weight loss may improve metabolic risk, it can further deplete lean mass and compromise physical function if not carefully managed