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13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

Incorporating ground flaxseeds into your meals, such as adding them to yogurt or smoothies, can be a simple way to boost your omega-3 intake and potentially support GLP-1 function

232(2): 4038 Mitchell SC, Zhang A, Smith RL, et al

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Acknowledgements We are grateful to members of our laboratory for helpful discussion and critical comments on the manuscript