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For instance, NO, a critical factor for vasodilation, is synthesized by endothelial NO synthase (eNOS) within endothelial cells [179,180,181,182,183]

Tetrahydrofolic acid, methyltetrahydrofolate, and other folic acid congeners are essential for the maintenance of normal erythropoiesis and are also required cofactors for the synthesis of purine and thymidylate nucleic acids

While NSAIDs reduce pain and inflammation, they also interfere with tissue repair processes