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While most people report positive effects while on GLP-1s, the experience isnt golden for everyone, says Vij

Nausea, vomiting, diarrhea, and constipation are all side effects that patients can experience

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Louwagie tells Endocrine News that that he and his co-authors would want clinicians to keep this potential side effect in mind for all patients presenting with signs of ketoacidosis while on tirzepatide

MMPs are the main proteases involved in the invasion and degradation of the anatomical barrier