10.1007/s40265-015-0493-8 25 ButlerA
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"However, information related to pregnancy appears in Section 8.1 and 8.3 of the prescribing information for both Ozempic and Wegovy." "I don't believe that we're going to see hideous long-term side effects but who wants to take the chance?" That information includes the following warning: "Based on animal reproduction studies, there may be potential risks to the fetus from exposure to semaglutide during pregnancy, [Ozempic and Wegovy] should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus." Said the company, "Pregnant women exposed to [Ozempic and Wegovy] and health care providers are encouraged to contact Novo Nordisk at 1-800-727-6500." Novo Nordisk also pointed out that while Wegovy and Ozempic both contain semaglutide, they are different products with different indications, dosages, prescribing information, titration schedules and delivery devices

Protocol Initiation: Treatment begins with conservative dosing that is gradually optimized based on symptom response and lab results