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However, the rapid adoption occurs against a backdrop of worsening obesity and diabetes epidemics, with significant geographic and racial disparities requiring targeted interventions ^28

Implication: lowest regulatory risk when routed through branded/manufacturer channels

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But like many systems in the body, it can become less reliable due to a variety of factors, including age, diet and other lifestyle habits

Methods Research was conducted for this systematic review using the PRISMA guidelines (Prisma, 2015[40])