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Both the GLP-1 and GIP receptors are expressed on neurons in the arcuate nucleus and other parts of the hypothalamus, and their activation reduce food intake and body weight ( These findings have promoted an interest to discover the CV benefits of this pharmacological class extending beyond its glycemic effect
While the conventional therapeutic applications of GLP-1RAs have primarily focused on metabolic disorders, their multifaceted neuroprotective properties and anti-inflammatory mechanisms present a distinctive therapeutic opportunity for ophthalmic pathologies, potentially offering direct ocular benefits beyond systemic metabolic control
Genetic control of splicing at SIRPG modulates risk of type 1 diabetes
Saudi J Biol Sci 29:103373 Alharthi WA, Hamza RZ, Elmahdi MM, Abuelzahab HS, Saleh H (2020) Selenium and L-carnitine ameliorate reproductive toxicity induced by cadmium in male mice
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