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These pathways have contributed to widespread marketing of TB-500 as a recovery-enhancing therapy (Gonzalez-Franquesa et al

The beneficial effects were dose-dependent without altering locomotion or anxiety

These include ACE inhibitors, angiotensin receptor blockers (ARBs), nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, the blood thinner heparin, and the antibiotic trimethoprim

The H-score is calculated as follows: H-score = (percentage of cells with weak intensity 1) + (percentage of cells with moderate intensity 2) + (percentage of cells with strong intensity 3), resulting in a final score ranging from 0 to 300

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Banatwala UESS, Health Science Reports (Vol