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F.2006Thioredoxin is required for deoxyribonucleotide pool maintenance during S phase

10.1016/j.bioorg.2020.104382 51 ChenX.DrewJ.BerneyW.LeiW

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Formation of inclusion bodies disrupts cell homeostasis, axonal transport, synaptic receptor activity, and neurotransmitter release (Ehlers, 2013), and also results in mitochondrial swelling and damage (Maharjan et al., 2014), impaired cell differentiation, degeneration, and neuronal death via apoptosis or necrosis (Schwartz and Ciechanover, 2009