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While not studied extensively, there appears to be a series of internal skin factors that are turned off by the GLP-1 drug that cause skin to look duller than usual, more wrinkled, and have more sun-induced pigmentation

In animal models, selective removal of these cells has been associated with improved tissue morphology and regenerative capacity

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95% CI, 0.75 to 1.23) or the rate of death (HR, 0.94

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