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If youre supplementing without baseline liver enzyme elevation or oxidative stress symptoms, you may not notice measurable changes

The phase 2 study in type 2 diabetes patients showed significant appetite reductions, but the overall weight loss was slightly lower than in the obesity-only trial (16.9% versus 24.2% at the highest doses over comparable timeframes)

High-dose B12 therapy can also boost nerve function and reduce pain

[DOI] [PMC free article] [PubMed] [Google Scholar] 174.Fernandez A.F., Sebti S., Wei Y., Zou Z., Shi M., McMillan K.L., He C., Ting T., Liu Y., Chiang W.C., et al

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