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Therefore, it has been observed that the antioxidant capacity found in the cellular matrix may become reduced in critical clinical conditions, including septic shock, cardiac bypass surgery, and reperfusion injury after organ transplantation, and renal dialysis [216]

In preclinical models it has been associated with cytoprotection , modulation of nitric-oxide pathways and angiogenesis , with reported activity across gastrointestinal, musculoskeletal and other tissues [1] [2]

Solution: Begin with a low dose and gradually increase under guidance

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