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This is typically telogen effluvium, a temporary shedding condition triggered by the physiological stress of rapid weight loss rather than a direct drug effect

Covalent inhibitors : Drugs such as the EGFR inhibitor Zegfrovy (sunvozertinib) , the HER2 inhibitor Hernexeos (zongertinib) , and the BTK inhibitor Wayrilz (rilzabrutinib) form covalent bonds with their targets to achieve sustained inhibition

In the Phase 3 TRIUMPH-4 trial, retatrutide at 12 mg produced 28.7% body weight loss at 68 weeks vs 2.1% for placebo

A more recent analysis showed more than nine million prescriptions for Wegovy and other injectable drugs used for weight loss were doled out in the last three months of 2022 The weight loss drug market is expanding rapidly, with a projected value of $100 billion by 2030

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