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By inhibiting NNMT, researchers can preserve NAD+ levels, enhance cellular energy capacity, promote fat utilization, and support metabolic healthall without exogenous NAD+ supplementation

Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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Use 1 to 2% concentrations rather than chasing the highest number

For example, take your multivitamin with breakfast and your calcium supplements with lunch to prevent calcium from affecting the absorption of other minerals such as iron, magnesium, copper, and zinc in the multivitamin

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