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Novo Nordisk published a cross-trial comparison claiming its Wegovy pill produced greater weight loss than Eli Lilly $LLY's newly approved obesity tablet Foundayo, raising the stakes as the two companies compete to shape prescribing trends in the oral GLP-1 market.

Eligibility is selective, with strict BMI, age, comorbidity, and previous-treatment criteria, and some participants receive placebo (a dummy version of the drug)

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GSK3 inhibitors GSK3 is a serine/threonine protein kinase involved in numerous cellular processes including glycogen metabolism [48]