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While generally safe, they should be used under medical supervision to avoid potential side effects or interaction.

Molecular docking experiments were conducted with four target proteins (COX-2, MMP-9, TNF-, and MPO) to explore the interaction between mesalamine (compound 36, Figure 26) and its coumarin derivative, MS-CU

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Extracellular UDP-glucose activates P2Y14 receptor and induces signal transducer and activator of transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes

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