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First, a T 2 -weighted MRI (T2WI) rapid acquisition with relaxation enhancement (RARE) (echo time (TE) = 54.39 ms, repetition time (TR) = 1800 ms, field of view (FOV) = 35 35 85 mm 3 , matrix size = 128 128) was performed

Additionally, the tumor microenvironment changes by immune cell infiltration, particularly macrophages with a tumor-promoting phenotype, which interact with adipocytes and cancer cells to support tumor progression [4,20]

Alternative types of extraction, such as ultrasound-assisted extraction, microwave-assisted extraction and supercritical fluid extraction have also been described [55, 56, 58,59,60]

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Acta Pharmacol Sin 38:241251 Santn-Mrquez R, Alarcn-Aguilar A, Lpez-Diazguerrero NE, Chondrogianni N, Knigsberg M (2019) Sulforaphane - role in aging and neurodegeneration