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In the context of protein oxidation, the relationship between AGEs and the generation of AOPPs is noteworthy (75)

Polysorbates are commonly used in medicine and foods

Int J Mol Sci 17:1234 Kim K, Jang H, Kim E, Kim H, Sung GY (2023) Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis

doi: 10.1016/j.neuropharm.2017.08.010 66 EsslingerCSCybulskiKARhoderickJF

Therefore, they lack sufficient regulatory value

The key principle is that any combination therapy should be initiated and monitored under close medical supervision, with dose adjustments made based on glucose monitoring results and individual patient response