Initial counselling Following the decision to prescribe a GLP-1RA, the patient should be counselled on injection techniques, dose titration, expected adverse effects (see Box 2) and when to seek help
GLP-1 is encoded by preproglucagon (gene name, Gcg ) and is expressed in neurons in the nucleus tractus solitarus, enteroendocrine L cells, and pancreatic alpha-cells ( Indeed, several early studies using GLP-1 immunoreactivity ( (137) ] and, therefore, called into question the physiological relevance of pancreatic GLP-1
Wegovy does not affect serotonin pathways
Tracy Norfleet, MD, FACP, notes: "Injection site reactions may get worse over the first 24 hours, and should improve thereafter
J.MannI
A healthy gut contains a balance of both beneficial and harmful bacteria